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(Created page with "== Cell types == What is a cell type? I do not know. We do not know. This wikibase is a shot at formalizing meanings for cell types and cell type descriptors. Properti...")
 
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== Cell types ==  
= Cell types =


What is a cell type?  
What is a cell type?  


I do not know. We do not know.  
This wikibase is a shot at formalizing meanings for cell types and cell type descriptors.  
 
== Formal criteria ==
The notion is that anything that any class of cells that fits the 3 following criteria is formally a cell type:
 
* The instances are rigorously defined (i.e. you have guidelines for telling wheter a cell is or isn't an instance of that class)
* The class' instances are present in a specific taxon
* The class is considered useful by any research project.  


This wikibase is a shot at formalizing meanings for cell types and cell type descriptors.  
Some subdefinitions help to organize it
 
== Subdefinitions ==
 
=== Cell archetype ===
A cell type defined for more than one species, e.g. "neuron")
 
=== Cell type ''strictu sensu'' ===
A cell type defined for one taxon (e.g. "human neuron")


Properties characterize a given class. There might be specific properties for definition. Or qualifiers to tag caracteristics that are necessary and sufficient to describe any given cell type.  
=== Cell infratype ===
A cell type defined for a taxon below the species level (e.g. "C57BL/6J  mice neuron")


The initial idea is that every cell classification is a cell type. Implementation challenges will help to solve differences and so on.
=== Technotype ===
A cell type that rigorously corresponds to what is being measured in a given experiment ("ex: CD4+ CD8- FACS-sorted C57BL/6J mice cell")

Revision as of 02:23, 7 August 2020

Cell types

What is a cell type?

This wikibase is a shot at formalizing meanings for cell types and cell type descriptors.

Formal criteria

The notion is that anything that any class of cells that fits the 3 following criteria is formally a cell type:

  • The instances are rigorously defined (i.e. you have guidelines for telling wheter a cell is or isn't an instance of that class)
  • The class' instances are present in a specific taxon
  • The class is considered useful by any research project.

Some subdefinitions help to organize it

Subdefinitions

Cell archetype

A cell type defined for more than one species, e.g. "neuron")

Cell type strictu sensu

A cell type defined for one taxon (e.g. "human neuron")

Cell infratype

A cell type defined for a taxon below the species level (e.g. "C57BL/6J mice neuron")

Technotype

A cell type that rigorously corresponds to what is being measured in a given experiment ("ex: CD4+ CD8- FACS-sorted C57BL/6J mice cell")